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What to do at maximum dose with inadequate results If you're at 15 mg tirzepatide for 12+ weeks after a full titration period, have addressed eating/sleep/alcohol/clinical factors, and still aren't progressing meaningfully, options include: Acknowledge a modest-response biology and shift focus to maintenance Trial enrollment for investigational drugs (retatrutide, others) - these are investigational and not FDA-approved
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If you’re not losing much weight while taking Ozempic, consider asking your healthcare provider about switching to another diabetes medication that supports weight loss, such as Mounjaro (tirzepatide)